Cytoplasmic phospholipase a2
Web"Cytoplasmic phospholipase A2 levels correlate with apoptosis in human colon tumorigenesis". Clin. Cancer Res. 11 (6): 2265–71. doi: 10.1158/1078-0432.CCR-04-1079. PMID 15788676. Yan W, Jenkins CM, Han X, et al. (2005). WebNational Center for Biotechnology Information
Cytoplasmic phospholipase a2
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WebJan 15, 2000 · The release of labeled AA was studied in parallel to the analysis of cPLA 2 levels and activity. [ 3 H]AA release from prelabeled neutrophils stimulated with 50 ng/mL …
WebCytoplasmic phospholipase A2 metabolites play a critical role in pulmonary tumor metastasis in mice. This study demonstrates that cPLA(2) metabolites play critical roles … WebApr 12, 1994 · In addition, the band that corresponds to phospholipase A2 is shifted upward in membrane isolated from neutrophils stimulated with fMet-Leu-Phe, suggesting that the enzyme has been altered, possibly phosphorylated, though not on tyrosine residues. A working hypothesis is presented.
WebMultiple forms of phospholipase A2 may be associated with the production of these metabolites; this study focused on the molecular mechanism(s) by which glucocorticoids control expression of the arachidonyl-selective, … WebMar 3, 2006 · Abstract Phagocytosis of non-opsonized microorganisms by macrophages initiates innate immune responses for host defense against infection. Cytosolic phospholipase A (2) is activated during phagocytosis, releasing arachidonic acid for production of eicosanoids, which initiate acute inflammation.
WebMay 5, 2005 · Introduction. Lipid requirements of the mammal are met by dietary intake and de novo synthesis; the omega-6 fatty acids (ω-6 FAs) are essential since they cannot be synthesized by mammals and must be supplied in the diet. Linoleic acid (LA) and its product, arachidonic acid (AA) are transformed into prostaglandins (PG) and thromboxanes (TX) …
WebOct 1, 2024 · Among them, cytoplasmic phospholipase A2 (cPLA2), the key enzyme of the pro-inflammatory mediator, was the most significantly down-regulated protein. And enriched KEGG pathway shown that PPAR-γ pathway was most involved. Taxifolin significantly reduced p-cPLA2 and increased PPAR-γ protein level in keratinocytes and … get help from microsoft 365WebDec 7, 2024 · Activation of phospholipase A2 (PLA2) is an essential prerequisite for GPVI stimulated thromboxane A2 (TXA2) generation that induces paracrine platelet activation … get help from hmrc if you need extra supportWebJun 18, 1999 · We further show that MIF regulates cytosolic phospholipase A 2 activity via a protein kinase A and ERK dependent pathway and that the glucocorticoid suppression of cytokine-induced cytoplasmic phospholipase A2 activity and arachidonic acid release can be reversed by the addition of recombinant MIF. These studies indicate that the … gethelpfromhere - infinite solutionsWebCytosolic phospholipase A2 antibody; Cytosolic phospholipase A2 group IVA antibody; Lysophospholipase antibody; MGC126350 antibody; PA24A_HUMAN antibody; … gethelpinfoWebMay 15, 1993 · Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis. PNAS Research Article Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis. get help from microsoftWebDec 8, 2024 · Summary This gene encodes a member of the cytosolic phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of phospholipids, releasing lysophospholipids and fatty acids. This enzyme may be associated with mitochondria and early endosomes. get help from outlook.comWebApr 12, 1994 · Cytoplasmic phospholipase A2 translocates to membrane fraction in human neutrophils activated by stimuli that phosphorylate mitogen-activated protein … christmas party nights chester 2022